CD4 T-Cell Memory Responses to Viral Infections of Humans Show Pronounced Immunodominance Independent of Duration or Viral Persistence

Little is known concerning immunodominance within the CD4 T-cell response to viral infections and its persistence into long-term memory. We tested CD4 T-cell reactivity against each viral protein in persons immunized with vaccinia virus (VV), either recently or more than 40 years ago, as a model sel...

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Detalhes bibliográficos
Main Authors: Jing, Lichen, Schiffer, Joshua T., Chong, Tiana M., Bruckner, Joseph J., Davies, D. Huw, Felgner, Phillip L., Haas, Juergen, Wald, Anna, Verjans, G. M. G. M., Koelle, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571405/
https://ncbi.nlm.nih.gov/pubmed/23255792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03047-12
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