Cross-presentation and genome-wide screening reveal candidate T cells antigens for a herpes simplex virus type 1 vaccine

Herpes simplex virus type 1 (HSV-1) not only causes painful recurrent oral-labial infections, it can also cause permanent brain damage and blindness. There is currently no HSV-1 vaccine. An effective vaccine must stimulate coordinated T cell responses, but the large size of the genome and the low fr...

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Detalhes bibliográficos
Main Authors: Jing, Lichen, Haas, Jürgen, Chong, Tiana M., Bruckner, Joseph J., Dann, Greg C., Dong, Lichun, Marshak, Joshua O., McClurkan, Christopher L., Yamamoto, Tori N., Bailer, Susanne M., Laing, Kerry J., Wald, Anna, Verjans, Georges M.G.M., Koelle, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Technical Advance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266794/
https://ncbi.nlm.nih.gov/pubmed/22214845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI60556
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