An Extremely Diverse CD4 Response to Vaccinia Virus in Humans Is Revealed by Proteome-Wide T-Cell Profiling

CD4 T cells are required for the maintenance and recall of antiviral CD8 T cells and for antibody responses. Little is known concerning the overall architecture of the CD4 response to complex microbial pathogens. In a whole-proteome approach, 180 predicted open reading frames (ORFs) in the vaccinia...

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Detalhes bibliográficos
Main Authors: Jing, Lichen, Davies, D. Huw, Chong, Tiana M., Chun, Sookhee, McClurkan, Christopher L., Huang, Jay, Story, Brian T., Molina, Douglas M., Hirst, Siddiqua, Felgner, Philip L., Koelle, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446988/
https://ncbi.nlm.nih.gov/pubmed/18480455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00453-08
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