Cross-priming utilizes antigen not available to the direct presentation pathway

CD8(+) T cells play a crucial role in protective immunity to viruses and tumours. Antiviral CD8(+) T cells are initially activated by professional antigen presenting cells (pAPCs) that are directly infected by viruses (direct-priming) or following uptake of exogenous antigen transferred from virus-i...

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Detalhes bibliográficos
Main Authors: Donohue, Keri B, Grant, Jean M, Tewalt, Eric F, Palmer, Douglas C, Theoret, Marc R, Restifo, Nicholas P, Norbury, Christopher C
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2006
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782342/
https://ncbi.nlm.nih.gov/pubmed/16764686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2006.02406.x
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