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IFN-γ-receptor signaling ameliorates transplant vasculopathy through attenuation of CD8(+) T-cell-mediated injury of vascular endothelial cells

Occlusive transplant vasculopathy (TV) is the major cause for chronic graft rejection. Since endothelial cells (EC) are the first graft cells encountered by activated host lymphocytes, it is important to delineate the molecular mechanisms that coordinate the interaction of EC with activated T cells....

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Detalhes bibliográficos
Main Authors: Bolinger, Beatrice, Engeler, Daniel, Krebs, Philippe, Miller, Simone, Firner, Sonja, Hoffmann, Matthias, Palmer, Douglas C., Restifo, Nicholas P., Tian, Yinghua, Clavien, Pierre-Alain, Ludewig, Burkhard
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247644/
https://ncbi.nlm.nih.gov/pubmed/20049875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939706
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