IFN-γ-receptor signaling ameliorates transplant vasculopathy through attenuation of CD8(+) T-cell-mediated injury of vascular endothelial cells

Occlusive transplant vasculopathy (TV) is the major cause for chronic graft rejection. Since endothelial cells (EC) are the first graft cells encountered by activated host lymphocytes, it is important to delineate the molecular mechanisms that coordinate the interaction of EC with activated T cells....

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Hlavní autoři: Bolinger, Beatrice, Engeler, Daniel, Krebs, Philippe, Miller, Simone, Firner, Sonja, Hoffmann, Matthias, Palmer, Douglas C., Restifo, Nicholas P., Tian, Yinghua, Clavien, Pierre-Alain, Ludewig, Burkhard
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247644/
https://ncbi.nlm.nih.gov/pubmed/20049875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939706
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