Treatment of transthyretin (TTR) amyloid cardiomyopathy with an antisense oligonucleotide inhibitor of TTR synthesis

Por Benson, Merrill D, Ackermann, Elizabeth J, Monia, Brett P
Publicado no Orphanet J Rare Dis (2015)

Genomic Analysis of wig-1 Pathways

Por Sedaghat, Yalda, Mazur, Curt, Sabripour, Mahyar, Hung, Gene, Monia, Brett P.
Publicado em 2012

Inhibition of telomerase by 2′-O-(2-methoxyethyl) RNA oligomers: effect of length, phosphorothioate substitution and time inside cells

Por Elayadi, Anissa N., Demieville, Andrea, Wancewicz, Edward V., Monia, Brett P., Corey, David R.
Publicado em 2001

Translational regulation of lipoprotein lipase in adipocytes: depletion of cellular protein kinase Cα activates binding of the C subunit of protein kinase A to the 3′-untranslated...

Por Unal, Resat, Pokrovskaya, Irina, Tripathi, Preeti, Monia, Brett P., Kern, Philip A., Ranganathan, Gouri
Publicado em 2008

Combination of Tmprss6- ASO and the iron chelator deferiprone improves erythropoiesis and reduces iron overload in a mouse model of beta-thalassemia intermedia

Por Casu, Carla, Aghajan, Mariam, Oikonomidou, Paraskevi Rea, Guo, Shuling, Monia, Brett P., Rivella, Stefano
Publicado no Haematologica (2016)

Inhibiting Gene Expression with Locked Nucleic Acids (LNAs) that Target Chromosomal DNA

Por Beane, Randall L., Ram, Rosalyn, Gabillet, Sylvie, Arar, Khalil, Monia, Brett P., Corey, David R.
Publicado em 2007

Critical role of stearoyl-CoA desaturase–1 (SCD1) in the onset of diet-induced hepatic insulin resistance

Por Gutiérrez-Juárez, Roger, Pocai, Alessandro, Mulas, Claudia, Ono, Hiraku, Bhanot, Sanjay, Monia, Brett P., Rossetti, Luciano
Publicado em 2006

Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia

Por McWhirter, John R., Neuteboom, Saskia T. C., Wancewicz, Edward V., Monia, Brett P., Downing, James R., Murre, Cornelis
Publicado em 1999

Severe impairment in liver insulin signaling fails to alter hepatic insulin action in conscious mice

Por Buettner, Christoph, Patel, Rima, Muse, Evan D., Bhanot, Sanjay, Monia, Brett P., McKay, Rob, Obici, Silvana, Rossetti, Luciano
Publicado em 2005

Antisense suppression of the nonsense mediated decay factor Upf3b as a potential treatment for diseases caused by nonsense mutations

Por Huang, Lulu, Low, Audrey, Damle, Sagar S., Keenan, Melissa M., Kuntz, Steven, Murray, Susan F., Monia, Brett P., Guo, Shuling
Publicado no Genome Biol (2018)

Antisense transcripts are targets for activating small RNAs

Por Schwartz, Jacob C, Younger, Scott T, Nguyen, Ngoc-Bich, Hardy, Daniel B, Monia, Brett P, Corey, David R, Janowski, Bethany A
Publicado em 2008

Peripheral Reduction of FGFR4 with Antisense Oligonucleotides Increases Metabolic Rate and Lowers Adiposity in Diet-Induced Obese Mice

Por Yu, Xing Xian, Watts, Lynnetta M., Manchem, Vara Prasad, Chakravarty, Kaushik, Monia, Brett P., McCaleb, Michael L., Bhanot, Sanjay
Publicado em 2013

Reducing TMPRSS6 ameliorates hemochromatosis and β-thalassemia in mice

Por Guo, Shuling, Casu, Carla, Gardenghi, Sara, Booten, Sheri, Aghajan, Mariam, Peralta, Raechel, Watt, Andy, Freier, Sue, Monia, Brett P., Rivella, Stefano
Publicado em 2013

Antisense oligonucleotide-mediated Dnm2 knockdown prevents and reverts myotubular myopathy in mice

Por Tasfaout, Hichem, Buono, Suzie, Guo, Shuling, Kretz, Christine, Messaddeq, Nadia, Booten, Sheri, Greenlee, Sarah, Monia, Brett P., Cowling, Belinda S., Laporte, Jocelyn
Publicado no Nat Commun (2017)

Role of resistin in diet-induced hepatic insulin resistance

Por Muse, Evan D., Obici, Silvana, Bhanot, Sanjay, Monia, Brett P., McKay, Robert A., Rajala, Michael W., Scherer, Philipp E., Rossetti, Luciano
Publicado em 2004

Antisense oligonucleotides containing locked nucleic acid improve potency but cause significant hepatotoxicity in animals

Por Swayze, Eric E., Siwkowski, Andrew M., Wancewicz, Edward V., Migawa, Michael T., Wyrzykiewicz, Tadeusz K., Hung, Gene, Monia, Brett P., Bennett, and C. Frank
Publicado em 2007

Using antisense technology to develop a novel therapy for α-1 antitrypsin deficient (AATD) liver disease and to model AATD lung disease

Por Guo, Shuling, Booten, Sheri L, Watt, Andrew, Alvarado, Luis, Freier, Susan M, Teckman, Jeffery H, McCaleb, Michael L, Monia, Brett P
Publicado em 2014

Factor XI Antisense Oligonucleotide for Prevention of Venous Thrombosis

Por Büller, Harry R., Bethune, Claudette, Bhanot, Sanjay, Gailani, David, Monia, Brett P., Raskob, Gary E., Segers, Annelise, Verhamme, Peter, Weitz, Jeffrey I.
Publicado no N Engl J Med (2014)

Selective depletion of plasma prekallikrein or coagulation factor XII inhibits thrombosis in mice without increased risk of bleeding

Por Revenko, Alexey S., Gao, Dacao, Crosby, Jeff R., Bhattacharjee, Gourab, Zhao, Chenguang, May, Chris, Gailani, David, Monia, Brett P., MacLeod, A. Robert
Publicado no Blood (2011)

Reduction in ocular complement factor B protein in mice and monkeys by systemic administration of factor B antisense oligonucleotide

Por Grossman, Tamar R., Carrer, Michele, Shen, Lijiang, Johnson, Robert B., Hettrick, Lisa A., Henry, Scott P., Monia, Brett P., McCaleb, Michael L.
Publicado no Mol Vis (2017)