The Puzzle of RNAs that Target Gene Promoters

Por Younger, Scott T., Corey, David R.
Publicado em 2009

Transcriptional gene silencing in mammalian cells by miRNA mimics that target gene promoters

Por Younger, Scott T., Corey, David R.
Publicado em 2011

'Lnc'-ing enhancers to MYC regulation

Por Younger, Scott T, Rinn, John L
Publicado em 2014

Transcriptional regulation by miRNA mimics that target sequences downstream of gene termini()

Por Younger, Scott T., Corey, David R.
Publicado no Mol Biosyst (2011)

Silent pericentromeric repeats speak out

Por Younger, Scott T., Rinn, John L.
Publicado no Proc Natl Acad Sci U S A (2015)

p53 regulates enhancer accessibility and activity in response to DNA damage

Por Younger, Scott T., Rinn, John L.
Publicado no Nucleic Acids Res (2017)

Identification of functional regulatory elements in the human genome using pooled CRISPR screens

Por Borys, Samantha M., Younger, Scott T.
Publicado no BMC Genomics (2020)

Predicting potential miRNA target sites within gene promoters

Por Younger, Scott T., Pertsemlidis, Alexander, Corey, David R.
Publicado em 2009

CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo

Por Shechner, David M., Hacisüleyman, Ezgi, Younger, Scott T., Rinn, John L.
Publicado no Nat Methods (2015)

Expediting rare disease diagnosis: a call to bridge the gap between clinical and functional genomics

Por Hartin, Samantha N., Means, John C., Alaimo, Joseph T., Younger, Scott T.
Publicado no Mol Med (2020)

Involvement of argonaute proteins in gene silencing and activation by RNAs complementary to a non-coding transcript at the progesterone receptor promoter

Por Chu, Yongjun, Yue, Xuan, Younger, Scott T., Janowski, Bethany A., Corey, David R.
Publicado em 2010

Integrative genomic analysis reveals widespread enhancer regulation by p53 in response to DNA damage

Por Younger, Scott T., Kenzelmann-Broz, Daniela, Jung, Heiyoun, Attardi, Laura D., Rinn, John L.
Publicado no Nucleic Acids Res (2015)

Regulation of Transcription by Small RNAs Complementary to Sequences Downstream from the 3’ Termini of Genes

Por Yue, Xuan, Schwartz, Jacob C., Younger, Scott T., Chu, Yongjun, Gagnon, Keith T., Elbashir, Sayda, Janowski, Bethany A., Corey, David R.
Publicado em 2010

Antisense transcripts are targets for activating small RNAs

Por Schwartz, Jacob C, Younger, Scott T, Nguyen, Ngoc-Bich, Hardy, Daniel B, Monia, Brett P, Corey, David R, Janowski, Bethany A
Publicado em 2008

Medin Oligomer Membrane Pore Formation: A Potential Mechanism of Vascular Dysfunction

Por Younger, Scott, Jang, Hyunbum, Davies, Hannah A., Niemiec, Martin J., Garcia, Joe G.N., Nussinov, Ruth, Migrino, Raymond Q., Madine, Jillian, Arce, Fernando T.
Publicado no Biophys J (2020)

Orthologous CRISPR-Cas9 enzymes for Combinatorial Genetic Screens

Por Najm, Fadi J, Strand, Christine, Donovan, Katherine F, Hegde, Mudra, Sanson, Kendall R, Vaimberg, Emma W, Sullender, Meagan E, Hartenian, Ella, Kalani, Zohra, Fusi, Nicolo, Listgarten, Jennifer, Younger, Scott T, Bernstein, Bradley E, Root, David E, Doench, John G
Publicado no Nat Biotechnol (2017)

Deubiquitinases maintain protein homeostasis and survival of cancer cells upon glutathione depletion

Por Harris, Isaac S., Endress, Jennifer E., Coloff, Jonathan L., Selfors, Laura M., McBrayer, Samuel K., Rosenbluth, Jennifer M., Takahashi, Nobuaki, Dhakal, Sabin, Koduri, Vidyasagar, Oser, Matthew G., Schauer, Nathan J., Doherty, Laura M., Hong, Andrew L., Kang, Yun Pyo, Younger, Scott T., Doench, John G., Hahn, William C., Buhrlage, Sara J., DeNicola, Gina M., Kaelin, William G., Brugge, Joan S.
Publicado no Cell Metab (2019)

Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets

Por Dempster, Joshua M., Pacini, Clare, Pantel, Sasha, Behan, Fiona M., Green, Thomas, Krill-Burger, John, Beaver, Charlotte M., Younger, Scott T., Zhivich, Victor, Najgebauer, Hanna, Allen, Felicity, Gonçalves, Emanuel, Shepherd, Rebecca, Doench, John G., Yusa, Kosuke, Vazquez, Francisca, Parts, Leopold, Boehm, Jesse S., Golub, Todd R., Hahn, William C., Root, David E., Garnett, Mathew J., Tsherniak, Aviad, Iorio, Francesco
Publicado no Nat Commun (2019)

Cells Lacking the RB1 Tumor Suppressor Gene are Hyperdependent on Aurora B Kinase for Survival

Por Oser, Matthew G., Fonseca, Raquel, Chakraborty, Abhishek A., Brough, Rachel, Spektor, Alexander, Jennings, Rebecca B., Flaifel, Abdallah, Novak, Jesse S., Gulati, Aditi, Buss, Elizabeth, Younger, Scott T., McBrayer, Samuel K., Cowley, Glenn S., Bonal, Dennis M., Nguyen, Quang-De, Brulle-Soumare, Laura, Taylor, Paula, Cairo, Stefano, Ryan, Colm J., Pease, Elizabeth J., Maratea, Kim, Travers, Jon, Root, David E., Signoretti, Sabina, Pellman, David, Ashton, Susan, Lord, Christopher J., Barry, Simon T., Kaelin, William G.
Publicado no Cancer Discov (2018)