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Antisense transcripts are targets for activating small RNAs

Agents that activate expression of specific genes to probe cellular pathways or alleviate disease would go beyond existing approaches for controlling gene expression. Duplex RNAs complementary to promoter regions can repress or activate gene expression. The mechanism of these promoter-directed antig...

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Detalhes bibliográficos
Main Authors: Schwartz, Jacob C, Younger, Scott T, Nguyen, Ngoc-Bich, Hardy, Daniel B, Monia, Brett P, Corey, David R, Janowski, Bethany A
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574822/
https://ncbi.nlm.nih.gov/pubmed/18604220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1444
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