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Antisense transcripts are targets for activating small RNAs

Agents that activate expression of specific genes to probe cellular pathways or alleviate disease would go beyond existing approaches for controlling gene expression. Duplex RNAs complementary to promoter regions can repress or activate gene expression. The mechanism of these promoter-directed antig...

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Bibliografiska uppgifter
Huvudupphovsmän: Schwartz, Jacob C, Younger, Scott T, Nguyen, Ngoc-Bich, Hardy, Daniel B, Monia, Brett P, Corey, David R, Janowski, Bethany A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574822/
https://ncbi.nlm.nih.gov/pubmed/18604220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1444
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