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Antisense transcripts are targets for activating small RNAs

Agents that activate expression of specific genes to probe cellular pathways or alleviate disease would go beyond existing approaches for controlling gene expression. Duplex RNAs complementary to promoter regions can repress or activate gene expression. The mechanism of these promoter-directed antig...

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Autori principali: Schwartz, Jacob C, Younger, Scott T, Nguyen, Ngoc-Bich, Hardy, Daniel B, Monia, Brett P, Corey, David R, Janowski, Bethany A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574822/
https://ncbi.nlm.nih.gov/pubmed/18604220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1444
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