Medin Oligomer Membrane Pore Formation: A Potential Mechanism of Vascular Dysfunction

Medin, a 50-amino-acid cleavage product of the milk fat globule-EGF factor 8 protein, is one of the most common forms of localized amyloid found in the vasculature of individuals older than 50 years. Medin induces endothelial dysfunction and vascular inflammation, yet despite its prevalence in the h...

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Bibliografiset tiedot
Julkaisussa:Biophys J
Päätekijät: Younger, Scott, Jang, Hyunbum, Davies, Hannah A., Niemiec, Martin J., Garcia, Joe G.N., Nussinov, Ruth, Migrino, Raymond Q., Madine, Jillian, Arce, Fernando T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Biophysical Society 2020
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264854/
https://ncbi.nlm.nih.gov/pubmed/32402244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.04.026
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