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Amyloidogenic medin induces endothelial dysfunction and vascular inflammation through the receptor for advanced glycation endproducts

AIMS: Medin is a common amyloidogenic protein in humans that accumulates in arteries with advanced age and has been implicated in vascular degeneration. Medin’s effect on endothelial function remains unknown. The aims are to assess medin’s effects on human arteriole endothelial function and identify...

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Detalhes bibliográficos
Publicado no:Cardiovasc Res
Main Authors: Migrino, Raymond Q., Davies, Hannah A., Truran, Seth, Karamanova, Nina, Franco, Daniel A., Beach, Thomas G., Serrano, Geidy E., Truong, Danh, Nikkhah, Mehdi, Madine, Jillian
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676393/
https://ncbi.nlm.nih.gov/pubmed/28859297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvx135
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