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Amyloidogenic medin induces endothelial dysfunction and vascular inflammation through the receptor for advanced glycation endproducts

AIMS: Medin is a common amyloidogenic protein in humans that accumulates in arteries with advanced age and has been implicated in vascular degeneration. Medin’s effect on endothelial function remains unknown. The aims are to assess medin’s effects on human arteriole endothelial function and identify...

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Vydáno v:Cardiovasc Res
Hlavní autoři: Migrino, Raymond Q., Davies, Hannah A., Truran, Seth, Karamanova, Nina, Franco, Daniel A., Beach, Thomas G., Serrano, Geidy E., Truong, Danh, Nikkhah, Mehdi, Madine, Jillian
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676393/
https://ncbi.nlm.nih.gov/pubmed/28859297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvx135
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