Nanoliposomes protect against human arteriole endothelial dysfunction induced by β-amyloid peptide

We tested whether nanoliposomes containing phosphatidylcholine, cholesterol and phosphatidic acid (NLPA) prevent β-amyloid 1-42 (Aβ42) fibrillation and Aβ42-induced human arteriole endothelial dysfunction. NLPA abolished Aβ42 fibril formation (thioflavin-T fluorescence/electron microscopy). In ex-vi...

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Detalles Bibliográficos
Publicado en:J Cereb Blood Flow Metab
Main Authors: Truran, Seth, Weissig, Volkmar, Madine, Jillian, Davies, Hannah A, Guzman-Villanueva, Diana, Franco, Daniel A, Karamanova, Nina, Burciu, Camelia, Serrano, Geidy, Beach, Thomas G, Migrino, Raymond Q
Formato: Artigo
Idioma:Inglês
Publicado: SAGE Publications 2015
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759678/
https://ncbi.nlm.nih.gov/pubmed/26661197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X15610134
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