Monosialoganglioside‐Containing Nanoliposomes Restore Endothelial Function Impaired by AL Amyloidosis Light Chain Proteins

BACKGROUND: Light chain amyloidosis (AL) is associated with high mortality, especially in patients with advanced cardiovascular involvement. It is caused by toxicity of misfolded light chain proteins (LC) in vascular, cardiac, and other tissues. There is no treatment to reverse LC tissue toxicity. W...

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Bibliografski detalji
Izdano u:J Am Heart Assoc
Glavni autori: Franco, Daniel A., Truran, Seth, Weissig, Volkmar, Guzman‐Villanueva, Diana, Karamanova, Nina, Senapati, Subhadip, Burciu, Camelia, Ramirez‐Alvarado, Marina, Blancas‐Mejia, Luis M., Lindsay, Stuart, Hari, Parameswaran, Migrino, Raymond Q.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Original Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937272/
https://ncbi.nlm.nih.gov/pubmed/27412900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.003318
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