JAK2 inhibitors do not affect stem cells present in the spleens of patients with myelofibrosis

Por Wang, Xiaoli, Ye, Fei, Tripodi, Joseph, Hu, Cing Siang, Qiu, Jiajing, Najfeld, Vesna, Novak, Jesse, Li, Yan, Rampal, Raajit, Hoffman, Ronald
Publicado no Blood (2014)

A Non-integrating Lentiviral Approach Overcomes Cas9-Induced Immune Rejection to Establish an Immunocompetent Metastatic Renal Cancer Model

Por Hu, Junhui, Schokrpur, Shiruyeh, Archang, Maani, Hermann, Kip, Sharrow, Allison C., Khanna, Prateek, Novak, Jesse, Signoretti, Sabina, Bhatt, Rupal S., Knudsen, Beatrice S., Xu, Hua, Wu, Lily
Publicado no Mol Ther Methods Clin Dev (2018)

Comprehensive analyses of tumor immunity: implications for cancer immunotherapy

Por Li, Bo, Severson, Eric, Pignon, Jean-Christophe, Zhao, Haoquan, Li, Taiwen, Novak, Jesse, Jiang, Peng, Shen, Hui, Aster, Jon C., Rodig, Scott, Signoretti, Sabina, Liu, Jun S., Liu, X. Shirley
Publicado no Genome Biol (2016)

pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependentmanner

Por Guo, Jianping, Chakraborty, Abhishek A., Liu, Pengda, Gan, Wenjian, Zheng, Xingnan, Inuzuka, Hiroyuki, Wang, Bin, Zhang, Jinfang, Zhang, Linli, Yuan, Min, Novak, Jesse, Cheng, Jin Q., Toker, Alex, Signoretti, Sabina, Zhang, Qing, Asara, John M., Kaelin, William G., Wei, Wenyi
Publicado no Science (2016)

HIF Activation Causes Synthetic Lethality Between the VHL Tumor Suppressor and the EZH1 Histone Methyltransferase

Por Chakraborty, Abhishek A., Nakamura, Eijiro, Qi, Jun, Creech, Amanda, Jaffe, Jacob D., Paulk, Joshiawa, Novak, Jesse S., Nagulapalli, Kshithija, McBrayer, Samuel K., Cowley, Glenn S., Pineda, Javier, Song, Jiaxi, Wang, Yaoyu E., Carr, Steven A., Root, David E., Signoretti, Sabina, Bradner, James E., Kaelin, William G.
Publicado no Sci Transl Med (2017)

Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase

Por McBrayer, Samuel K., Olenchock, Benjamin A., DiNatale, Gabriel J., Shi, Diana D., Khanal, Januka, Jennings, Rebecca B., Novak, Jesse S., Oser, Matthew G., Robbins, Alissa K., Modiste, Rebecca, Bonal, Dennis, Moslehi, Javid, Bronson, Roderick T., Neuberg, Donna, Nguyen, Quang-De, Signoretti, Sabina, Losman, Julie-Aurore, Kaelin, William G.
Publicado no Proc Natl Acad Sci U S A (2018)

Cabozantinib eradicates advanced murine prostate cancer by activating anti-tumor innate immunity

Por Patnaik, Akash, Swanson, Kenneth D., Csizmadia, Eva, Solanki, Aniruddh, Landon-Brace, Natalie, Gehring, Marina P., Helenius, Katja, Olson, Brian M., Pyzer, Athalia R., Wang, Lily C., Elemento, Olivier, Novak, Jesse, Thornley, Thomas B., Asara, John M., Montaser, Laleh, Timmons, Joshua J., Morgan, Todd M., Wang, Yugang, Levantini, Elena, Clohessy, John G., Kelly, Kathleen, Pandolfi, Pier Paolo, Rosenblatt, Jacalyn M., Avigan, David E., Ye, Huihui, Karp, Jeffrey M., Signoretti, Sabina, Balk, Steven P., Cantley, Lewis C.
Publicado no Cancer Discov (2017)