JAK2 inhibitors do not affect stem cells present in the spleens of patients with myelofibrosis

Dysregulation of Janus kinase (JAK)–signal transducer and activator of transcription signaling is central to the pathogenesis of myelofibrosis (MF). JAK2 inhibitor therapy in MF patients results in a rapid reduction of the degree of splenomegaly, yet the mechanism underlying this effect remains unkn...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Blood
Main Authors: Wang, Xiaoli, Ye, Fei, Tripodi, Joseph, Hu, Cing Siang, Qiu, Jiajing, Najfeld, Vesna, Novak, Jesse, Li, Yan, Rampal, Raajit, Hoffman, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224194/
https://ncbi.nlm.nih.gov/pubmed/25193869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-558015
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados