Loading...

Transcriptional gene silencing in mammalian cells by miRNA mimics that target gene promoters

Synthetic small duplex RNAs that are fully complementary to gene promoters can silence transcription in mammalian cells. microRNAs (miRNAs) are endogenous small regulatory RNAs that sequence specifically regulate gene expression. We have developed a computational method to identify potential miRNA t...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Younger, Scott T., Corey, David R.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141263/
https://ncbi.nlm.nih.gov/pubmed/21427083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr155
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!