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Transcriptional gene silencing in mammalian cells by miRNA mimics that target gene promoters
Synthetic small duplex RNAs that are fully complementary to gene promoters can silence transcription in mammalian cells. microRNAs (miRNAs) are endogenous small regulatory RNAs that sequence specifically regulate gene expression. We have developed a computational method to identify potential miRNA t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3141263/ https://ncbi.nlm.nih.gov/pubmed/21427083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr155 |
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