Regulation of miRNA-mediated gene silencing by miRNA precursors

Processing of miRNAs from their precursors to the biologically active mature form is regulated during development and cancer. We show that mouse precursor-miR-151 can bind to and compete with mature miR-151-5p and miR-151-3p for binding sites contained within the complementary regions of the E2f6 mR...

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Bibliographic Details
Published in:Nat Struct Mol Biol
Main Authors: Roy-Chaudhuri, Biswajoy, Valdmanis, Paul N., Zhang, Yue, Wang, Qing, Luo, Qingjun, Kay, Mark A.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244528/
https://ncbi.nlm.nih.gov/pubmed/25086740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2862
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