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p53 regulates enhancer accessibility and activity in response to DNA damage

The tumor suppressor p53 is a well-characterized transcription factor that can bind gene promoters and regulate target gene transcription in response to DNA damage. Recent studies, however, have revealed that p53 binding events occur predominantly within regulatory enhancer elements. The effect of p...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Younger, Scott T., Rinn, John L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622327/
https://ncbi.nlm.nih.gov/pubmed/28973438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx577
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