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p53 regulates enhancer accessibility and activity in response to DNA damage

The tumor suppressor p53 is a well-characterized transcription factor that can bind gene promoters and regulate target gene transcription in response to DNA damage. Recent studies, however, have revealed that p53 binding events occur predominantly within regulatory enhancer elements. The effect of p...

詳細記述

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書誌詳細
出版年:Nucleic Acids Res
主要な著者: Younger, Scott T., Rinn, John L.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622327/
https://ncbi.nlm.nih.gov/pubmed/28973438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx577
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