Unraveling oxyntomodulin, GLP1's enigmatic brother

door Pocai, Alessandro
Gepubliceerd in 2012

Action and therapeutic potential of oxyntomodulin()

door Pocai, Alessandro
Gepubliceerd in 2013

Glucagon signaling in the heart: Activation or inhibition?()

door Pocai, Alessandro
Gepubliceerd in Mol Metab (2014)

Modulation of Glucagon Signaling: A Metabolic Approach for Heart Failure?

door Pocai, Alessandro
Gepubliceerd in JACC Basic Transl Sci (2019)

Critical role of STAT3 in leptin’s metabolic actions

door Buettner, Christoph, Pocai, Alessandro, Muse, Evan D., Etgen, Anne M., Myers, Martin G., Rossetti, Luciano
Gepubliceerd in 2006

Critical role of stearoyl-CoA desaturase–1 (SCD1) in the onset of diet-induced hepatic insulin resistance

door Gutiérrez-Juárez, Roger, Pocai, Alessandro, Mulas, Claudia, Ono, Hiraku, Bhanot, Sanjay, Monia, Brett P., Rossetti, Luciano
Gepubliceerd in 2006

Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats

door Pocai, Alessandro, Lam, Tony K.T., Obici, Silvana, Gutierrez-Juarez, Roger, Muse, Evan D., Arduini, Arduino, Rossetti, Luciano
Gepubliceerd in 2006

Hypothalamic Leucine Metabolism Regulates Liver Glucose Production

door Su, Ya, Lam, Tony K.T., He, Wu, Pocai, Alessandro, Bryan, Joseph, Aguilar-Bryan, Lydia, Gutiérrez-Juárez, Roger
Gepubliceerd in 2012

Activation of hypothalamic S6 kinase mediates diet-induced hepatic insulin resistance in rats

door Ono, Hiraku, Pocai, Alessandro, Wang, Yuhua, Sakoda, Hideyuki, Asano, Tomoichiro, Backer, Jonathan M., Schwartz, Gary J., Rossetti, Luciano
Gepubliceerd in 2008

GRK Inhibition Potentiates Glucagon-Like Peptide-1 Action

door Lee, Seunghun P., Qi, Jenson, Xu, Guozhang, Rankin, Matthew M., Littrell, James, Xu, June Zhi, Bakaj, Ivona, Pocai, Alessandro
Gepubliceerd in Front Endocrinol (Lausanne) (2021)

Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia

door El-Osta, Assam, Brasacchio, Daniella, Yao, Dachun, Pocai, Alessandro, Jones, Peter L., Roeder, Robert G., Cooper, Mark E., Brownlee, Michael
Gepubliceerd in 2008

Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia

door El-Osta, Assam, Brasacchio, Daniella, Yao, Dachun, Pocai, Alessandro, Jones, Peter L., Roeder, Robert G., Cooper, Mark E., Brownlee, Michael
Gepubliceerd in 2008

The Irs1 Branch of the Insulin Signaling Cascade Plays a Dominant Role in Hepatic Nutrient Homeostasis

door Guo, Shaodong, Copps, Kyle D., Dong, Xiaocheng, Park, Sunmin, Cheng, Zhiyong, Pocai, Alessandro, Rossetti, Luciano, Sajan, Mini, Farese, Robert V., White, Morris F.
Gepubliceerd in 2009

Acute hemodynamic and renal effects of glucagon-like peptide 1 analog and dipeptidyl peptidase-4 inhibitor in rats

door Zhou, Xiaoyan, Huang, Chin-hu, Lao, Julie, Pocai, Alessandro, Forrest, Gail, Price, Olga, Roy, Sophie, Kelley, David E, Sullivan, Kathleen A, Forrest, Michael J
Gepubliceerd in Cardiovasc Diabetol (2015)

Leptin controls adipose tissue lipogenesis via central, STAT3–independent mechanisms

door Buettner, Christoph, Muse, Evan D, Cheng, Andrew, Chen, Linghong, Scherer, Thomas, Pocai, Alessandro, Su, Kai, Cheng, Bob, Li, Xiasong, Harvey-White, Judith, Schwartz, Gary J, Kunos, George, Rossetti, Luciano
Gepubliceerd in 2008

The Glucagon Receptor Is Involved in Mediating the Body Weight-Lowering Effects of Oxyntomodulin

door Kosinski, Jennifer R., Hubert, James, Carrington, Paul E., Chicchi, Gary G., Mu, James, Miller, Corey, Cao, Jin, Bianchi, Elisabetta, Pessi, Antonello, SinhaRoy, Ranabir, Marsh, Donald J., Pocai, Alessandro
Gepubliceerd in 2012

Glucagon like receptor 1/ glucagon dual agonist acutely enhanced hepatic lipid clearance and suppressed de novo lipogenesis in mice

door More, Vijay R., Lao, Julie, McLaren, David G., Cumiskey, Anne-Marie, Murphy, Beth Ann, Chen, Ying, Previs, Stephen, Stout, Steven, Patel, Rajesh, Satapati, Santhosh, Li, Wenyu, Kowalik, Edward, Szeto, Daphne, Nawrocki, Andrea, Pocai, Alessandro, Wang, Liangsu, Carrington, Paul
Gepubliceerd in PLoS One (2017)

A comparative study of the binding properties, dipeptidyl peptidase‐4 (DPP‐4) inhibitory activity and glucose‐lowering efficacy of the DPP‐4 inhibitors alogliptin, linagliptin, sax...

door Berger, Joel P., SinhaRoy, Ranabir, Pocai, Alessandro, Kelly, Theresa M., Scapin, Giovanna, Gao, Ying‐Duo, Pryor, Kelly Ann D., Wu, Joseph K., Eiermann, George J., Xu, Shiyao S., Zhang, Xiaoping, Tatosian, Daniel A., Weber, Ann E., Thornberry, Nancy A., Carr, Richard D.
Gepubliceerd in Endocrinol Diabetes Metab (2017)

Discovery of a GPR40 Superagonist: The Impact of Aryl Propionic Acid α-Fluorination

door Huang, Hui, Meegalla, Sanath K., Lanter, James C., Winters, Michael P., Zhao, Shuyuan, Littrell, James, Qi, Jenson, Rady, Brian, Lee, Paul S., Liu, Jianying, Martin, Tonya, Lam, Wing W., Xu, Fran, Lim, Heng Keang, Wilde, Thomas, Silva, Jose, Otieno, Monicah, Pocai, Alessandro, Player, Mark R.
Gepubliceerd in ACS Med Chem Lett (2018)

Glucagon-Like Peptide 1/Glucagon Receptor Dual Agonism Reverses Obesity in Mice

door Pocai, Alessandro, Carrington, Paul E., Adams, Jennifer R., Wright, Michael, Eiermann, George, Zhu, Lan, Du, Xiaobing, Petrov, Aleksandr, Lassman, Michael E., Jiang, Guoqiang, Liu, Franklin, Miller, Corey, Tota, Laurie M., Zhou, Gaochao, Zhang, Xiaoping, Sountis, Michael M., Santoprete, Alessia, Capito', Elena, Chicchi, Gary G., Thornberry, Nancy, Bianchi, Elisabetta, Pessi, Antonello, Marsh, Donald J., SinhaRoy, Ranabir
Gepubliceerd in 2009