A radical explanation for glucose-induced β cell dysfunction

by Brownlee, Michael
Published 2003

Foreword

by Brownlee, Michael
Published 2003

Hyperglycemia-Induced Reactive Oxygen Species Increase Expression of the Receptor for Advanced Glycation End Products (RAGE) and RAGE Ligands

by Yao, Dachun, Brownlee, Michael
Published 2010

Oxidative stress and diabetic complications

by Giacco, Ferdinando, Brownlee, Michael
Published 2010

Molecular and Cellular Mechanisms of Cardiovascular Disorders in Diabetes

by Shah, Manasi S., Brownlee, Michael
Published in Circ Res (2016)

Mitochondrial reactive oxygen species in the pathogenesis of early diabetic nephropathy

by Nishikawa, Takeshi, Brownlee, Michael, Araki, Eiichi
Published in J Diabetes Investig (2015)

Susceptibility to Apoptosis in Insulin-like Growth Factor-I Receptor-deficient Brown Adipocytes

by Valverde, Angela M., Mur, Cecilia, Brownlee, Michael, Benito, Manuel
Published 2004

Diabetic Retinopathy: Targeting Vasoregression

by Hammes, Hans-Peter, Feng, Yuxi, Pfister, Frederick, Brownlee, Michael
Published 2011

Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site

by Du, Xue Liang, Edelstein, Diane, Dimmeler, Stefanie, Ju, Qida, Sui, Chengyu, Brownlee, Michael
Published 2001

Insulin resistance reduces arterial prostacyclin synthase and eNOS activities by increasing endothelial fatty acid oxidation

by Du, Xueliang, Edelstein, Diane, Obici, Silvana, Higham, Ninon, Zou, Ming-Hui, Brownlee, Michael
Published 2006

Glucagon-Like Peptide-1 Cleavage Product GLP-1(9-36) Amide Rescues Synaptic Plasticity and Memory Deficits in Alzheimer's Disease Model Mice

by Ma, Tao, Du, Xueliang, Pick, Joseph E., Sui, Guangzhi, Brownlee, Michael, Klann, Eric
Published 2012

Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells

by Du, Xueliang, Matsumura, Takeshi, Edelstein, Diane, Rossetti, Luciano, Zsengellér, Zsuzsanna, Szabó, Csaba, Brownlee, Michael
Published 2003

Knockdown of Glyoxalase 1 Mimics Diabetic Nephropathy in Nondiabetic Mice

by Giacco, Ferdinando, Du, Xueliang, D’Agati, Vivette D., Milne, Ross, Sui, Guangzhi, Geoffrion, Michele, Brownlee, Michael
Published 2014

Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosyl...

by Du, Xue-Liang, Edelstein, Diane, Rossetti, Luciano, Fantus, Ivan George, Goldberg, Howard, Ziyadeh, Fuad, Wu, Jie, Brownlee, Michael
Published 2000

Decreasing Intracellular Superoxide Corrects Defective Ischemia-induced New Vessel Formation in Diabetic Mice

by Ceradini, Daniel J., Yao, Dachun, Grogan, Raymon H., Callaghan, Matthew J., Edelstein, Diane, Brownlee, Michael, Gurtner, Geoffrey C.
Published 2008

Hyperglycemia Impairs Proteasome Function by Methylglyoxal

by Queisser, Markus A., Yao, Dachun, Geisler, Sven, Hammes, Hans-Peter, Lochnit, Günter, Schleicher, Erwin D., Brownlee, Michael, Preissner, Klaus T.
Published 2010

Advanced glycation endproduct (AGE) accumulation and AGE receptor (RAGE) up‐regulation contribute to the onset of diabetic cardiomyopathy

by Ma, Heng, Li, Shi‐Yan, Xu, Peisheng, Babcock, Sara A., Dolence, E. Kurt, Brownlee, Michael, Li, Ji, Ren, Jun
Published 2008

Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia

by El-Osta, Assam, Brasacchio, Daniella, Yao, Dachun, Pocai, Alessandro, Jones, Peter L., Roeder, Robert G., Cooper, Mark E., Brownlee, Michael
Published 2008

Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia

by El-Osta, Assam, Brasacchio, Daniella, Yao, Dachun, Pocai, Alessandro, Jones, Peter L., Roeder, Robert G., Cooper, Mark E., Brownlee, Michael
Published 2008

Persistent Oxidative Stress Due to Absence of Uncoupling Protein 2 Associated with Impaired Pancreatic β-Cell Function

by Pi, Jingbo, Bai, Yushi, Daniel, Kiefer W., Liu, Dianxin, Lyght, Otis, Edelstein, Diane, Brownlee, Michael, Corkey, Barbara E., Collins, Sheila
Published 2009