Restoration of insulin receptor improves diabetic phenotype in T2DM mice

Por Wang, Yichen, Zhou, Heather, Palyha, Oksana, Mu, James
Publicado no JCI Insight (2019)

Potentiation of Insulin-Mediated Glucose Lowering without Elevated Hypoglycemia Risk by a Small Molecule Insulin Receptor Modulator

Por Wu, Margaret, Dai, Ge, Yao, Jun, Hoyt, Scott, Wang, Liangsu, Mu, James
Publicado no PLoS One (2015)

AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation

Por Zong, Haihong, Ren, Jian Ming, Young, Lawrence H., Pypaert, Marc, Mu, James, Birnbaum, Morris J., Shulman, Gerald I.
Publicado em 2002

PANIC-ATTAC: A Mouse Model for Inducible and Reversible β-Cell Ablation

Por Wang, Zhao V., Mu, James, Schraw, Todd D., Gautron, Laurent, Elmquist, Joel K., Zhang, Bei B., Brownlee, Michael, Scherer, Philipp E.
Publicado em 2008

GLUT4, AMP kinase, but not the insulin receptor, are required for hepatoportal glucose sensor–stimulated muscle glucose utilization

Por Burcelin, Rémy, Crivelli, Valerie, Perrin, Christophe, Costa, Anabela Da, Mu, James, Kahn, Barbara B., Birnbaum, Morris J., Kahn, C. Ronald, Vollenweider, Peter, Thorens, Bernard
Publicado em 2003

AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury

Por Russell, Raymond R., Li, Ji, Coven, David L., Pypaert, Marc, Zechner, Christoph, Palmeri, Monica, Giordano, Frank J., Mu, James, Birnbaum, Morris J., Young, Lawrence H.
Publicado em 2004

In Situ Forming Injectable Thermoresponsive Hydrogels for Controlled Delivery of Biomacromolecules

Por Dutta, Kingshuk, Das, Ritam, Ling, Jing, Monibas, Rafael Mayoral, Carballo-Jane, Ester, Kekec, Ahmet, Feng, Danqing Dennis, Lin, Songnian, Mu, James, Saklatvala, Robert, Thayumanavan, S., Liang, Yingkai
Publicado no ACS Omega (2020)

The Glucagon Receptor Is Involved in Mediating the Body Weight-Lowering Effects of Oxyntomodulin

Por Kosinski, Jennifer R., Hubert, James, Carrington, Paul E., Chicchi, Gary G., Mu, James, Miller, Corey, Cao, Jin, Bianchi, Elisabetta, Pessi, Antonello, SinhaRoy, Ranabir, Marsh, Donald J., Pocai, Alessandro
Publicado em 2012

Anti-Diabetic Efficacy and Impact on Amino Acid Metabolism of GRA1, a Novel Small-Molecule Glucagon Receptor Antagonist

Por Mu, James, Qureshi, Sajjad A., Brady, Edward J., Muise, Eric S., Candelore, Mari Rios, Jiang, Guoqiang, Li, Zhihua, Wu, Margaret S., Yang, Xiaodong, Dallas-Yang, Qing, Miller, Corey, Xiong, Yusheng, Langdon, Ronald B., Parmee, Emma R., Zhang, Bei B.
Publicado em 2012

A glucose-responsive insulin therapy protects animals against hypoglycemia

Por Yang, Ruojing, Wu, Margaret, Lin, Songnian, Nargund, Ravi P., Li, Xinghai, Kelly, Theresa, Yan, Lin, Dai, Ge, Qian, Ying, Dallas-yang, Qing, Fischer, Paul A., Cui, Yan, Shen, Xiaolan, Huo, Pei, Feng, Danqing Dennis, Erion, Mark D., Kelley, David E., Mu, James
Publicado no JCI Insight (2018)

The AMP-activated protein kinase α2 catalytic subunit controls whole-body insulin sensitivity

Por Viollet, Benoit, Andreelli, Fabrizio, Jørgensen, Sebastian B., Perrin, Christophe, Geloen, Alain, Flamez, Daisy, Mu, James, Lenzner, Claudia, Baud, Olivier, Bennoun, Myriam, Gomas, Emmanuel, Nicolas, Gaël, Wojtaszewski, Jørgen F.P., Kahn, Axel, Carling, David, Schuit, Frans C., Birnbaum, Morris J., Richter, Erik A., Burcelin, Rémy, Vaulont, Sophie
Publicado em 2003

Downstream Signaling Pathways in Mouse Adipose Tissues Following Acute In Vivo Administration of Fibroblast Growth Factor 21

Por Muise, Eric S., Souza, Sandra, Chi, An, Tan, Yejun, Zhao, Xuemei, Liu, Franklin, Dallas-yang, Qing, Wu, Margaret, Sarr, Tim, Zhu, Lan, Guo, Hongbo, Li, Zhihua, Li, Wenyu, Hu, Weiwen, Jiang, Guoqiang, Paweletz, Cloud P., Hendrickson, Ronald C., Thompson, John R., Mu, James, Berger, Joel P., Mehmet, Huseyin
Publicado em 2013

FGF21 Analogs of Sustained Action Enabled by Orthogonal Biosynthesis Demonstrate Enhanced Antidiabetic Pharmacology in Rodents

Por Mu, James, Pinkstaff, Jason, Li, Zhihua, Skidmore, Lillian, Li, Nina, Myler, Heather, Dallas-Yang, Qing, Putnam, Anna-Maria, Yao, Jun, Bussell, Stuart, Wu, Margaret, Norman, Thea C., Rodriguez, Carlos G., Kimmel, Bruce, Metzger, Joseph M., Manibusan, Anthony, Lee, Darin, Zaller, Dennis M., Zhang, Bei B., DiMarchi, Richard D., Berger, Joel P., Axelrod, Douglas W.
Publicado em 2012

Erratum. Engineering Glucose Responsiveness Into Insulin. Diabetes 2018;67:299–308

Por Kaarsholm, Niels C., Lin, Songnian, Yan, Lin, Kelly, Theresa, van Heek, Margaret, Mu, James, Wu, Margaret, Dai, Ge, Cui, Yan, Zhu, Yonghua, Carballo-Jane, Ester, Reddy, Vijay, Zafian, Peter, Huo, Pei, Shi, Shuai, Antochshuk, Valentyn, Ogawa, Aimie, Liu, Franklin, Souza, Sandra C., Seghezzi, Wolfgang, Duffy, Joseph L., Erion, Mark, Nargund, Ravi P., Kelley, David E.
Publicado no Diabetes (2018)