AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation

Mitochondrial biogenesis is a critical adaptation to chronic energy deprivation, yet the signaling mechanisms responsible for this response are poorly understood. To examine the role of AMP-activated protein kinase (AMPK), an evolutionarily conserved fuel sensor, in mitochondrial biogenesis we studi...

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Detalhes bibliográficos
Principais autores: Zong, Haihong, Ren, Jian Ming, Young, Lawrence H., Pypaert, Marc, Mu, James, Birnbaum, Morris J., Shulman, Gerald I.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC138551/
https://ncbi.nlm.nih.gov/pubmed/12444247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.252625599
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