Discovery of Highly Selective and Potent HDAC3 Inhibitors Based on a 2-Substituted Benzamide Zinc Binding Group

Yazar: Liu, Jian, Yu, Younong, Kelly, Joseph, Sha, Deyou, Alhassan, Abdul-Basit, Yu, Wensheng, Maletic, Milana M., Duffy, Joseph L., Klein, Daniel J., Holloway, M. Katharine, Carroll, Steve, Howell, Bonnie J., Barnard, Richard J. O., Wolkenberg, Scott, Kozlowski, Joseph A.
Yayımlandı ACS Med Chem Lett (2020)

Discovery of Novel Indoline Cholesterol Ester Transfer Protein Inhibitors (CETP) through a Structure-Guided Approach

Yazar: Wilson, Jonathan E., Kurukulasuriya, Ravi, Reibarkh, Mikhail, Reiter, Maud, Zwicker, Aaron, Zhao, Kake, Zhang, Fengqi, Anand, Rajan, Colandrea, Vincent J., Cumiskey, Anne-Marie, Crespo, Alejandro, Duffy, Ruth A., Murphy, Beth Ann, Mitra, Kaushik, Johns, Douglas G., Duffy, Joseph L., Vachal, Petr
Yayımlandı ACS Med Chem Lett (2016)

Optimization of Preclinical Metabolism for Somatostatin Receptor Subtype 5-Selective Antagonists

Yazar: Liu, Weiguo, Hussain, Zahid, Zang, Yi, Sweis, Ramzi F., Romero, F. Anthony, Finke, Paul E., Moningka, Remond, Bao, Jianming, Plotkin, Michael A., Shang, Jin, Dingley, Karen H., Salituro, Gino, Murphy, Beth Ann, Howard, Andrew D., Ujjainwalla, Feroze, Wood, Harold B., Duffy, Joseph L.
Yayımlandı ACS Med Chem Lett (2018)

Improved Stability of Proline-Derived Direct Thrombin Inhibitors through Hydroxyl to Heterocycle Replacement

Yazar: Chobanian, Harry R., Pio, Barbara, Guo, Yan, Shen, Hong, Huffman, Mark A., Madeira, Maria, Salituro, Gino, Terebetski, Jenna L., Ormes, James, Jochnowitz, Nina, Hoos, Lizbeth, Zhou, Yuchen, Lewis, Dale, Hawes, Brian, Mitnaul, Lyndon, O’Neill, Kim, Ellsworth, Kenneth, Wang, Liangsu, Biftu, Tesfaye, Duffy, Joseph L.
Yayımlandı ACS Med Chem Lett (2015)

Selective Class I HDAC Inhibitors Based on Aryl Ketone Zinc Binding Induce HIV-1 Protein for Clearance

Yazar: Liu, Jian, Kelly, Joseph, Yu, Wensheng, Clausen, Dane, Yu, Younong, Kim, Hyunjin, Duffy, Joseph L., Chung, Christine C., Myers, Robert W., Carroll, Steve, Klein, Daniel J., Fells, James, Holloway, M. Katharine, Wu, Jin, Wu, Guoxin, Howell, Bonnie J., Barnard, Richard J. O., Kozlowski, Joseph A.
Yayımlandı ACS Med Chem Lett (2020)

Discovery and Pharmacology of a Novel Somatostatin Subtype 5 (SSTR5) Antagonist: Synergy with DPP-4 Inhibition

Yazar: Liu, Weiguo, Shao, Pengcheng P., Liang, Gui-Bai, Bawiec, John, He, Jiafang, Aster, Susan D., Wu, Margaret, Chicchi, Garry, Wang, John, Tsao, Kwei-Lan, Shang, Jin, Salituro, Gino, Zhou, Yun-Ping, Li, Cai, Akiyama, Taro E., Metzger, Daniel E., Murphy, Beth Ann, Howard, Andrew D., Weber, Ann E., Duffy, Joseph L.
Yayımlandı ACS Med Chem Lett (2018)

Erratum. Engineering Glucose Responsiveness Into Insulin. Diabetes 2018;67:299–308

Yazar: Kaarsholm, Niels C., Lin, Songnian, Yan, Lin, Kelly, Theresa, van Heek, Margaret, Mu, James, Wu, Margaret, Dai, Ge, Cui, Yan, Zhu, Yonghua, Carballo-Jane, Ester, Reddy, Vijay, Zafian, Peter, Huo, Pei, Shi, Shuai, Antochshuk, Valentyn, Ogawa, Aimie, Liu, Franklin, Souza, Sandra C., Seghezzi, Wolfgang, Duffy, Joseph L., Erion, Mark, Nargund, Ravi P., Kelley, David E.
Yayımlandı Diabetes (2018)

Improved Ca(v)2.2 Channel Inhibitors through a gem-Dimethylsulfone Bioisostere Replacement of a Labile Sulfonamide

Yazar: Shao, Pengcheng P., Ye, Feng, Chakravarty, Prasun K., Herrington, James B., Dai, Ge, Bugianesi, Randal M., Haedo, Rodolfo J., Swensen, Andrew M., Warren, Vivien A., Smith, McHardy M., Garcia, Maria L., McManus, Owen B., Lyons, Kathryn A., Li, Xiaohua, Green, Mitchell, Jochnowitz, Nina, McGowan, Erin, Mistry, Shruti, Sun, Shu-Yu, Abbadie, Catherine, Kaczorowski, Gregory J., Duffy, Joseph L.
Baskı/Yayın Bilgisi 2013

Inhibition of O-GlcNAcase leads to elevation of O-GlcNAc tau and reduction of tauopathy and cerebrospinal fluid tau in rTg4510 mice

Yazar: Hastings, Nicholas B., Wang, Xiaohai, Song, Lixin, Butts, Brent D., Grotz, Diane, Hargreaves, Richard, Fred Hess, J., Hong, Kwok-Lam Karen, Huang, Cathy Ruey-Ruey, Hyde, Lynn, Laverty, Maureen, Lee, Julie, Levitan, Diane, Lu, Sherry X., Maguire, Maureen, Mahadomrongkul, Veeravan, McEachern, Ernest J., Ouyang, Xuesong, Rosahl, Thomas W., Selnick, Harold, Stanton, Michaela, Terracina, Giuseppe, Vocadlo, David J., Wang, Ganfeng, Duffy, Joseph L., Parker, Eric M., Zhang, Lili
Yayımlandı Mol Neurodegener (2017)