Synthesis of HDAC Inhibitor Libraries via Microscale Workflow

по Dykstra, Kevin D., Streckfuss, Eric, Liu, Min, Liu, Jian, Yu, Younong, Wang, Ming, Kozlowski, Joseph A., Myers, Robert W., Buevich, Alexei V., Maletic, Milana M., Vachal, Petr, Krska, Shane W.
Опубликовано в: ACS Med Chem Lett (2021)

Discovery of Highly Selective and Potent HDAC3 Inhibitors Based on a 2-Substituted Benzamide Zinc Binding Group

по Liu, Jian, Yu, Younong, Kelly, Joseph, Sha, Deyou, Alhassan, Abdul-Basit, Yu, Wensheng, Maletic, Milana M., Duffy, Joseph L., Klein, Daniel J., Holloway, M. Katharine, Carroll, Steve, Howell, Bonnie J., Barnard, Richard J. O., Wolkenberg, Scott, Kozlowski, Joseph A.
Опубликовано в: ACS Med Chem Lett (2020)

Selective Class I HDAC Inhibitors Based on Aryl Ketone Zinc Binding Induce HIV-1 Protein for Clearance

по Liu, Jian, Kelly, Joseph, Yu, Wensheng, Clausen, Dane, Yu, Younong, Kim, Hyunjin, Duffy, Joseph L., Chung, Christine C., Myers, Robert W., Carroll, Steve, Klein, Daniel J., Fells, James, Holloway, M. Katharine, Wu, Jin, Wu, Guoxin, Howell, Bonnie J., Barnard, Richard J. O., Kozlowski, Joseph A.
Опубликовано в: ACS Med Chem Lett (2020)

Discovery of SCH 900188: A Potent Hepatitis C Virus NS5B Polymerase Inhibitor Prodrug As a Development Candidate

по Chen, Kevin X., Venkatraman, Srikanth, Anilkumar, Gopinadhan N., Zeng, Qingbei, Lesburg, Charles A., Vibulbhan, Bancha, Velazquez, Francisco, Chan, Tin-Yau, Bennet, Frank, Jiang, Yueheng, Pinto, Patrick, Huang, Yuhua, Selyutin, Oleg, Agrawal, Sony, Huang, Hsueh-Cheng, Li, Cheng, Cheng, Kuo-Chi, Shih, Neng-Yang, Kozlowski, Joseph A., Rosenblum, Stuart B., Njoroge, F. George
Опубликовано 2013

Discovery of 8-Amino-imidazo[1,5-a]pyrazines as Reversible BTK Inhibitors for the Treatment of Rheumatoid Arthritis

по Liu, Jian, Guiadeen, Deodial, Krikorian, Arto, Gao, Xiaolei, Wang, James, Boga, Sobhana Babu, Alhassan, Abdul-Basit, Yu, Younong, Vaccaro, Henry, Liu, Shilan, Yang, Chundao, Wu, Hao, Cooper, Alan, de Man, Jos, Kaptein, Allard, Maloney, Kevin, Hornak, Viktor, Gao, Ying-Duo, Fischmann, Thierry O., Raaijmakers, Hans, Vu-Pham, Diep, Presland, Jeremy, Mansueto, My, Xu, Zangwei, Leccese, Erica, Zhang-Hoover, Jie, Knemeyer, Ian, Garlisi, Charles G., Bays, Nathan, Stivers, Peter, Brandish, Philip E., Hicks, Alexandra, Kim, Ronald, Kozlowski, Joseph A.
Опубликовано в: ACS Med Chem Lett (2015)