Selective Class I HDAC Inhibitors Based on Aryl Ketone Zinc Binding Induce HIV-1 Protein for Clearance

[Image: see text] HIV persistence in latently infected, resting CD4(+) T cells is broadly considered a barrier to eradicate HIV. Activation of the provirus using latency-reversing agents (LRAs) followed by immune-mediated clearance to purge reservoirs has been touted as a promising therapeutic appro...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:ACS Med Chem Lett
Main Authors: Liu, Jian, Kelly, Joseph, Yu, Wensheng, Clausen, Dane, Yu, Younong, Kim, Hyunjin, Duffy, Joseph L., Chung, Christine C., Myers, Robert W., Carroll, Steve, Klein, Daniel J., Fells, James, Holloway, M. Katharine, Wu, Jin, Wu, Guoxin, Howell, Bonnie J., Barnard, Richard J. O., Kozlowski, Joseph A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Chemical Society 2020
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7357218/
https://ncbi.nlm.nih.gov/pubmed/32676157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00302
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla