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Accounting for Strong Ligand Sensitivity in Pd-Catalyzed α-Arylation of Enolates from Ketones, Esters, and Nitroalkanes

The mechanism of the Pd-catalyzed α-arylation of three model enolates is studied focusing on a analysis of their very different reactivity. In particular, the low reactivity of nitronates under standard arylation conditions and their high sensitivity to the nature of catalytic system is addressed. T...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Tcyrulnikov, Sergei, Kozlowski, Marisa C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061083/
https://ncbi.nlm.nih.gov/pubmed/31994879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.9b03203
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