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Computational Analysis of Enantioselective Pd-Catalyzed α-Arylation of Ketones

[Image: see text] The direct α-arylation of carbonyl compounds emerged over the last two decades as a straightforward method for the formation of C(sp(3))–C(sp(2)) bonds. Mechanistic studies suggested a classical cross-coupling catalytic cycle. This consists of oxidative addition of the aryl halide...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Orlandi, Manuel, Licini, Giulia
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8009508/
https://ncbi.nlm.nih.gov/pubmed/32786644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.0c01768
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