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Enantioselective α-Arylation of Ketones with Aryl Triflates Catalyzed by Difluorphos Complexes of Palladium and Nickel

The asymmetric α-arylation of ketones with aryl triflates is described, and the use of this electrophile with nickel and palladium catalysts containing a segphos derivative increases substantially the scope of highly enantioselective arylations of ketone enolates. The combination of aryl triflates a...

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Autors principals: Liao, Xuebin, Weng, Zhiqiang, Hartwig, John F.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2551326/
https://ncbi.nlm.nih.gov/pubmed/18076166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja074453g
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