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Synthesis of substituted isoquinolines utilizing palladium-catalyzed α-arylation of ketones
The utilization of sequential palladium-catalyzed α-arylation and cyclization reactions provides a general approach to an array of isoquinolines and their corresponding N-oxides. This methodology allows the convergent combination of readily available precursors in a regioselective manner and in exce...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3406859/ https://ncbi.nlm.nih.gov/pubmed/22753504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206532109 |
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