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Nickel-catalyzed enantioselective arylation of pyridine
We report an enantioselective Ni-catalyzed cross coupling of arylzinc reagents with pyridinium ions formed in situ from pyridine and a chloroformate. This reaction provides enantioenriched 2-aryl-1,2-dihydropyridine products that can be elaborated to numerous piperidine derivatives with little or no...
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Publicado no: | Chem Sci |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Royal Society of Chemistry
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5207490/ https://ncbi.nlm.nih.gov/pubmed/28058106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc00702c |
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