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Nickel-catalyzed enantioselective vinylation of aryl 2-azaallyl anions

A unique enantioselective nickel-catalyzed vinylation of 2-azaallyl anions is advanced for the first time. This method affords diverse vinyl aryl methyl amines with high enantioselectivities, which are frequently occurring scaffolds in natural products and medications. This C–H functionalization met...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Chem Sci
Hauptverfasser: Duan, Shengzu, Deng, Guogang, Zi, Yujin, Wu, Xiaomei, Tian, Xun, Liu, Zhengfen, Li, Minyan, Zhang, Hongbin, Yang, Xiaodong, Walsh, Patrick J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Royal Society of Chemistry 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8115067/
https://ncbi.nlm.nih.gov/pubmed/34084440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1sc00972a
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