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Enantioselective nickel-catalyzed arylative and alkenylative intramolecular 1,2-allylations of tethered allene–ketones

The enantioselective nickel-catalyzed reaction of tethered allene–ketones with (hetero)arylboronic acids or potassium vinyltrifluoroborate is described. Carbonickelation of the allene gives allylnickel species, which undergo cyclization by 1,2-allylation to produce chiral tertiary-alcohol-containing...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Di Sanza, Riccardo, Nguyen, Thi Le Nhon, Iqbal, Naeem, Argent, Stephen P., Lewis, William, Lam, Hon Wai
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8157472/
https://ncbi.nlm.nih.gov/pubmed/34084403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc05246a
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