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Enantioselective Nickel‐Catalyzed anti‐Arylmetallative Cyclizations onto Acyclic Ketones

Domino reactions involving nickel‐catalyzed additions of (hetero)arylboronic acids to alkynes, followed by cyclization of the alkenylnickel intermediates onto tethered acyclic ketones to give chiral tertiary‐alcohol‐containing products in high enantioselectivities, are described. The reversible E/Z...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Green, Harley, Argent, Stephen P., Lam, Hon Wai
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048927/
https://ncbi.nlm.nih.gov/pubmed/33533065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202100143
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