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Enantioselective Nickel‐Catalyzed anti‐Arylmetallative Cyclizations onto Acyclic Ketones

Domino reactions involving nickel‐catalyzed additions of (hetero)arylboronic acids to alkynes, followed by cyclization of the alkenylnickel intermediates onto tethered acyclic ketones to give chiral tertiary‐alcohol‐containing products in high enantioselectivities, are described. The reversible E/Z...

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Bibliografske podrobnosti
izdano v:Chemistry
Main Authors: Green, Harley, Argent, Stephen P., Lam, Hon Wai
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048927/
https://ncbi.nlm.nih.gov/pubmed/33533065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202100143
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