Enantioselective Nickel-Catalyzed Mizoroki-Heck Cyclizations to Generate Quaternary Stereocenters

The development of enantioselective carbon-carbon bond couplings catalyzed by non-precious metals is highly desirable in terms of cost-efficiency and sustainability. The first nickel-catalyzed enantioselective Mizoroki-Heck coupling is reported. This transformation is accomplished via mild reaction...

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Veröffentlicht in:Org Lett
Hauptverfasser: Desrosiers, Jean-Nicolas, Wen, Jialin, Tcyrulnikov, Sergei, Biswas, Soumik, Qu, Bo, Hie, Liana, Kurouski, Dmitry, Wu, Ling, Grinberg, Nelu, Haddad, Nizar, Busacca, Carl A., Yee, Nathan K., Song, Jinhua J., Garg, Neil K., Zhang, Xumu, Kozlowski, Marisa C., Senanayake, Chris H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5634709/
https://ncbi.nlm.nih.gov/pubmed/28604006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b01054
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