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Enantioselective Dehydrogenative Heck Arylations of Trisubstituted Alkenes with Indoles to Construct Quaternary Stereocenters

An enantioselective, intermolecular dehydrogenative Heck arylation of trisubstituted alkenes to construct remote quaternary stereocenters has been developed. Using a new chiral pyridine oxazoline ligand, good to high enantioselectivity is achieved for various combinations of indole derivatives and t...

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Bibliografski detalji
Izdano u:J Am Chem Soc
Glavni autori: Zhang, Chun, Santiago, Celine B., Crawford, Jennifer M., Sigman, Matthew S.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039010/
https://ncbi.nlm.nih.gov/pubmed/26624236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b11335
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