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Enantioselective Dehydrogenative Heck Arylations of Trisubstituted Alkenes with Indoles to Construct Quaternary Stereocenters

An enantioselective, intermolecular dehydrogenative Heck arylation of trisubstituted alkenes to construct remote quaternary stereocenters has been developed. Using a new chiral pyridine oxazoline ligand, good to high enantioselectivity is achieved for various combinations of indole derivatives and t...

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書目詳細資料
發表在:J Am Chem Soc
Main Authors: Zhang, Chun, Santiago, Celine B., Crawford, Jennifer M., Sigman, Matthew S.
格式: Artigo
語言:Inglês
出版: 2015
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039010/
https://ncbi.nlm.nih.gov/pubmed/26624236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b11335
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