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Enantioselective Narasaka–Heck cyclizations: synthesis of tetrasubstituted nitrogen-bearing stereocenters

The first examples of highly enantioselective Narasaka–Heck cyclizations are described. A SPINOL-derived P,N-ligand system enables Pd-catalyzed 5-exo cyclization of a range of oxime esters with sterically diverse trisubstituted alkenes to generate dihydropyrroles containing tetrasubstituted nitrogen...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Chem Sci
Prif Awduron: Race, Nicholas J., Faulkner, Adele, Fumagalli, Gabriele, Yamauchi, Takayuki, Scott, James S., Rydén-Landergren, Marie, Sparkes, Hazel A., Bower, John F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Royal Society of Chemistry 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390761/
https://ncbi.nlm.nih.gov/pubmed/28451314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc04466b
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