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Recent developments in the use of aza-Heck cyclizations for the synthesis of chiral N-heterocycles

Aza-Heck cyclizations are an emerging method for the construction of chiral N-heterocyclic systems. In these processes, an activated N–O bond replaces the C–X bond (X = halide, OTf) used in conventional Heck reactions, with the associated aza-Pd(ii)-intermediate engaging pendant alkenes in a Heck-li...

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Pubblicato in:Chem Sci
Autori principali: Race, Nicholas J., Hazelden, Ian R., Faulkner, Adele, Bower, John F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Royal Society of Chemistry 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5606024/
https://ncbi.nlm.nih.gov/pubmed/28959424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc01480e
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