Pyrrolidines and Piperidines by Ligand‐Enabled Aza‐Heck Cyclizations and Cascades of N‐(Pentafluorobenzoyloxy)carbamates

Ligand‐enabled aza‐Heck cyclizations and cascades of N‐(pentafluorobenzoyloxy)carbamates are described. These studies encompass the first examples of efficient non‐biased 6‐exo aza‐Heck cyclizations. The methodology provides direct and flexible access to carbamate protected pyrrolidines and piperidi...

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Publicado en:Angew Chem Int Ed Engl
Autores principales: Hazelden, Ian R., Carmona, Rafaela C., Langer, Thomas, Pringle, Paul G., Bower, John F.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2018
Materias:
Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969259/
https://ncbi.nlm.nih.gov/pubmed/29488677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201801109
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