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Pyrrolidines and Piperidines by Ligand‐Enabled Aza‐Heck Cyclizations and Cascades of N‐(Pentafluorobenzoyloxy)carbamates

Ligand‐enabled aza‐Heck cyclizations and cascades of N‐(pentafluorobenzoyloxy)carbamates are described. These studies encompass the first examples of efficient non‐biased 6‐exo aza‐Heck cyclizations. The methodology provides direct and flexible access to carbamate protected pyrrolidines and piperidi...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Hazelden, Ian R., Carmona, Rafaela C., Langer, Thomas, Pringle, Paul G., Bower, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969259/
https://ncbi.nlm.nih.gov/pubmed/29488677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201801109
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