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Mizoroki–Heck Cyclizations of Amide Derivatives for the Introduction of Quaternary Centers
We report the non-decarbonylative Mizoroki–Heck reactions of amide derivatives. The transformation relies on the use of nickel catalysis and proceeds using sterically hindered tri- and tetrasubstituted olefins to give products containing quaternary centers. The resulting polycyclic or spirocyclic pr...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5669036/ https://ncbi.nlm.nih.gov/pubmed/28467029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201703174 |
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