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Accounting for Strong Ligand Sensitivity in Pd-Catalyzed α-Arylation of Enolates from Ketones, Esters, and Nitroalkanes

The mechanism of the Pd-catalyzed α-arylation of three model enolates is studied focusing on a analysis of their very different reactivity. In particular, the low reactivity of nitronates under standard arylation conditions and their high sensitivity to the nature of catalytic system is addressed. T...

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Veröffentlicht in:J Org Chem
Hauptverfasser: Tcyrulnikov, Sergei, Kozlowski, Marisa C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061083/
https://ncbi.nlm.nih.gov/pubmed/31994879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.9b03203
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