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Pd-Catalyzed α-Arylation of Trimethylsilyl Enolates of α,α-Difluoroacetamides

[Image: see text] We report the arylation and heteroarylation of α,α-difluoro-α-(trimethylsilyl)acetamides with aryl and heteroaryl bromides catalyzed by an air- and moisture-stable palladacyclic complex containing P(t-Bu)(2)Cy as ligand. A broad range of electronically varied aryl and heteroaryl br...

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Detalhes bibliográficos
Main Authors: Ge, Shaozhong, Arlow, Sophie I., Mormino, Michael G., Hartwig, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210146/
https://ncbi.nlm.nih.gov/pubmed/25254966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja508590k
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