Expression, purification and crystallization of human 5-lipoxygenase-activating protein with leukotriene-biosynthesis inhibitors

Por Xu, Shihua, McKeever, Brian M., Wisniewski, Douglas, Miller, Douglas K., Spencer, Robert H., Chu, Lin, Ujjainwalla, Feroze, Yamin, Ting-Ting, Evans, Jilly F., Becker, Joseph W., Ferguson, Andrew D.
Publicado em 2007

Discovery of Chromane Propionic Acid Analogues as Selective Agonists of GPR120 with in Vivo Activity in Rodents

Por Adams, Gregory L., Velazquez, Francisco, Jayne, Charles, Shah, Unmesh, Miao, Shouwu, Ashley, Eric R., Madeira, Maria, Akiyama, Taro E., Di Salvo, Jerry, Suzuki, Takao, Wang, Nengxue, Truong, Quang, Gilbert, Eric, Zhou, Dan, Verras, Andreas, Kirkland, Melissa, Pachanski, Michele, Powles, Maryann, Yin, Wu, Ujjainwalla, Feroze, Venkatraman, Srikanth, Edmondson, Scott D.
Publicado no ACS Med Chem Lett (2016)

Discovery of Spirocyclic Aldosterone Synthase Inhibitors as Potential Treatments for Resistant Hypertension

Por Petrilli, Whitney L., Hoyt, Scott B., London, Clare, McMasters, Daniel, Verras, Andreas, Struthers, Mary, Cully, Doris, Wisniewski, Thomas, Ren, Ning, Bopp, Charlene, Sok, Andrea, Chen, Qing, Li, Ying, Tung, Elaine, Tang, Wei, Salituro, Gino, Knemeyer, Ian, Karanam, Bindhu, Clemas, Joseph, Zhou, Gaochao, Gibson, Jack, Shipley, Carrie Ann, MacNeil, Douglas J., Duffy, Ruth, Tata, James R., Ujjainwalla, Feroze, Ali, Amjad, Xiong, Yusheng
Publicado no ACS Med Chem Lett (2016)

The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1)

Por Garcia-Calvo, Margarita, Lisnock, JeanMarie, Bull, Herbert G., Hawes, Brian E., Burnett, Duane A., Braun, Matthew P., Crona, James H., Davis, Harry R., Dean, Dennis C., Detmers, Patricia A., Graziano, Michael P., Hughes, Meredith, MacIntyre, D. Euan, Ogawa, Anthony, O'Neill, Kim A., Iyer, Sai Prasad N., Shevell, Diane E., Smith, Marsha M., Tang, Yui S., Makarewicz, Amanda M., Ujjainwalla, Feroze, Altmann, Scott W., Chapman, Kevin T., Thornberry, Nancy A.
Publicado em 2005

Discovery and Optimization of a Novel Triazole Series of GPR142 Agonists for the Treatment of Type 2 Diabetes

Por Guo, Liangqin, Parker, Dann L., Zang, Yi, Sweis, Ramzi F., Liu, Weiguo, Sherer, Edward C., Buist, Nicole, Terebetski, Jenna, Kelly, Terri, Bugianesi, Randal, Priest, Birgit T., Dingley, Karen H., Li, Xiaofang, Mitelman, Stan, Salituro, Gino, Trujillo, Maria E., Pachanski, Michele, Kirkland, Melissa, Powles, Mary Ann, Eiermann, George J., Feng, Yue, Shang, Jin, Howard, Andrew D., Ujjainwalla, Feroze, Sinz, Christopher J., Debenham, John S., Edmondson, Scott D., Nargund, Ravi P., Hagmann, William K., Li, Derun
Publicado no ACS Med Chem Lett (2016)

Design, Synthesis, and Evaluation of Novel and Selective G-protein Coupled Receptor 120 (GPR120) Spirocyclic Agonists

Por Cox, Jason M., Chu, Hong D., Chelliah, Mariappan V., Debenham, John S., Eagen, Keith, Lan, Ping, Lombardo, Matthew, London, Clare, Plotkin, Michael A., Shah, Unmesh, Sun, Zhongxiang, Vaccaro, Henry M., Venkatraman, Srikanth, Suzuki, Takao, Wang, Nengxue, Ashley, Eric R., Crespo, Alejandro, Madeira, Maria, Leung, Dennis H., Alleyne, Candice, Ogawa, Aimie M., Souza, Sarah, Thomas-Fowlkes, Brande, Di Salvo, Jerry, Weinglass, Adam, Kirkland, Melissa, Pachanski, Michele, Powles, Mary Ann, Tozzo, Effie, Akiyama, Taro E., Ujjainwalla, Feroze, Tata, James R., Sinz, Christopher J.
Publicado no ACS Med Chem Lett (2016)