Ion channels

Por Fermini, Bernard, Priest, Birgit T.
Publicado em 2008

Phenotypic screening in the 21st century

Por Priest, Birgit T., Erdemli, Gul
Publicado no Front Pharmacol (2014)

Subtype-selective sodium channel blockers promise a new era of pain research

Por Priest, Birgit T., Kaczorowski, Gregory J.
Publicado em 2007

Cardiac ion channels

Por Priest, Birgit T, McDermott, Jeff S
Publicado no Channels (Austin) (2015)

Inflammatory mediator-induced modulation of GABA(A) currents in human sensory neurons

Por Zhang, Xiulin, Lee, Kwan-Yeop, Priest, Birgit T., Belfer, Inna, Gold, Michael S.
Publicado no Neuroscience (2015)

Ion Channels as Drug Targets: The Next GPCRs

Por Kaczorowski, Gregory J., McManus, Owen B., Priest, Birgit T., Garcia, Maria L.
Publicado em 2008

Protein Kinase C enhances human sodium channel hNav1.7 resurgent currents via a serine residue in the domain III–IV linker

Por Tan, Zhi-Yong, Priest, Birgit T., Krajewski, Jeffrey L., Knopp, Kelly L., Nisenbaum, Eric S., Cummins, Theodore R.
Publicado no FEBS Lett (2014)

Tetrodotoxin-Resistant Sodium Channels in Sensory Neurons Generate Slow Resurgent Currents That Are Enhanced by Inflammatory Mediators

Por Tan, Zhi-Yong, Piekarz, Andrew D., Priest, Birgit T., Knopp, Kelly L., Krajewski, Jeffrey L., McDermott, Jeff S., Nisenbaum, Eric S., Cummins, Theodore R.
Publicado em 2014

Biophysical and pharmacological properties of the voltage-gated potassium current of human pancreatic β-cells

Por Herrington, James, Sanchez, Manuel, Wunderler, Denize, Yan, Lizhen, Bugianesi, Randal M, Dick, Ivy E, Clark, Sam A, Brochu, Richard M, Priest, Birgit T, Kohler, Martin G, McManus, Owen B
Publicado em 2005

Contribution of the tetrodotoxin-resistant voltage-gated sodium channel Na(V)1.9 to sensory transmission and nociceptive behavior

Por Priest, Birgit T., Murphy, Beth A., Lindia, Jill A., Diaz, Carmen, Abbadie, Catherine, Ritter, Amy M., Liberator, Paul, Iyer, Leslie M., Kash, Shera F., Kohler, Martin G., Kaczorowski, Gregory J., MacIntyre, D. Euan, Martin, William J.
Publicado em 2005

Discovery of Selective Small Molecule ROMK Inhibitors as Potential New Mechanism Diuretics

Por Tang, Haifeng, Walsh, Shawn P., Yan, Yan, de Jesus, Reynalda K., Shahripour, Aurash, Teumelsan, Nardos, Zhu, Yuping, Ha, Sookhee, Owens, Karen A., Thomas-Fowlkes, Brande S., Felix, John P., Liu, Jessica, Kohler, Martin, Priest, Birgit T., Bailey, Timothy, Brochu, Richard, Alonso-Galicia, Magdalena, Kaczorowski, Gregory J., Roy, Sophie, Yang, Lihu, Mills, Sander G., Garcia, Maria L., Pasternak, Alexander
Publicado em 2012

Discovery of MK-7145, an Oral Small Molecule ROMK Inhibitor for the Treatment of Hypertension and Heart Failure

Por Tang, Haifeng, Zhu, Yuping, Teumelsan, Nardos, Walsh, Shawn P., Shahripour, Aurash, Priest, Birgit T., Swensen, Andrew M., Felix, John P., Brochu, Richard M., Bailey, Timothy, Thomas-Fowlkes, Brande, Pai, Lee-Yuh, Hampton, Caryn, Corona, Aaron, Hernandez, Melba, Metzger, Joseph, Forrest, Michael, Zhou, Xiaoyan, Owens, Karen, Tong, Vincent, Parmee, Emma, Roy, Sophie, Kaczorowski, Gregory J., Yang, Lihu, Alonso-Galicia, Magdalena, Garcia, Maria L., Pasternak, Alexander
Publicado no ACS Med Chem Lett (2016)

Discovery and Optimization of a Novel Triazole Series of GPR142 Agonists for the Treatment of Type 2 Diabetes

Por Guo, Liangqin, Parker, Dann L., Zang, Yi, Sweis, Ramzi F., Liu, Weiguo, Sherer, Edward C., Buist, Nicole, Terebetski, Jenna, Kelly, Terri, Bugianesi, Randal, Priest, Birgit T., Dingley, Karen H., Li, Xiaofang, Mitelman, Stan, Salituro, Gino, Trujillo, Maria E., Pachanski, Michele, Kirkland, Melissa, Powles, Mary Ann, Eiermann, George J., Feng, Yue, Shang, Jin, Howard, Andrew D., Ujjainwalla, Feroze, Sinz, Christopher J., Debenham, John S., Edmondson, Scott D., Nargund, Ravi P., Hagmann, William K., Li, Derun
Publicado no ACS Med Chem Lett (2016)

Discovery of a Potent and Selective ROMK Inhibitor with Pharmacokinetic Properties Suitable for Preclinical Evaluation

Por Walsh, Shawn P., Shahripour, Aurash, Tang, Haifeng, Teumelsan, Nardos, Frie, Jessica, Zhu, Yuping, Priest, Birgit T., Swensen, Andrew M., Liu, Jessica, Margulis, Michael, Visconti, Richard, Weinglass, Adam, Felix, John P., Brochu, Richard M., Bailey, Timothy, Thomas-Fowlkes, Brande, Alonso-Galicia, Magdalena, Zhou, Xiaoyan, Pai, Lee-Yuh, Corona, Aaron, Hampton, Caryn, Hernandez, Melba, Bentley, Ross, Chen, Jing, Shah, Kashmira, Metzger, Joseph, Forrest, Michael, Owens, Karen, Tong, Vincent, Ha, Sookhee, Roy, Sophie, Kaczorowski, Gregory J., Yang, Lihu, Parmee, Emma, Garcia, Maria L., Sullivan, Kathleen, Pasternak, Alexander
Publicado no ACS Med Chem Lett (2015)