Biophysical and pharmacological properties of the voltage-gated potassium current of human pancreatic β-cells

Por Herrington, James, Sanchez, Manuel, Wunderler, Denize, Yan, Lizhen, Bugianesi, Randal M, Dick, Ivy E, Clark, Sam A, Brochu, Richard M, Priest, Birgit T, Kohler, Martin G, McManus, Owen B
Publicado em 2005

Discovery of MK-7145, an Oral Small Molecule ROMK Inhibitor for the Treatment of Hypertension and Heart Failure

Por Tang, Haifeng, Zhu, Yuping, Teumelsan, Nardos, Walsh, Shawn P., Shahripour, Aurash, Priest, Birgit T., Swensen, Andrew M., Felix, John P., Brochu, Richard M., Bailey, Timothy, Thomas-Fowlkes, Brande, Pai, Lee-Yuh, Hampton, Caryn, Corona, Aaron, Hernandez, Melba, Metzger, Joseph, Forrest, Michael, Zhou, Xiaoyan, Owens, Karen, Tong, Vincent, Parmee, Emma, Roy, Sophie, Kaczorowski, Gregory J., Yang, Lihu, Alonso-Galicia, Magdalena, Garcia, Maria L., Pasternak, Alexander
Publicado no ACS Med Chem Lett (2016)

Discovery of a Potent and Selective ROMK Inhibitor with Pharmacokinetic Properties Suitable for Preclinical Evaluation

Por Walsh, Shawn P., Shahripour, Aurash, Tang, Haifeng, Teumelsan, Nardos, Frie, Jessica, Zhu, Yuping, Priest, Birgit T., Swensen, Andrew M., Liu, Jessica, Margulis, Michael, Visconti, Richard, Weinglass, Adam, Felix, John P., Brochu, Richard M., Bailey, Timothy, Thomas-Fowlkes, Brande, Alonso-Galicia, Magdalena, Zhou, Xiaoyan, Pai, Lee-Yuh, Corona, Aaron, Hampton, Caryn, Hernandez, Melba, Bentley, Ross, Chen, Jing, Shah, Kashmira, Metzger, Joseph, Forrest, Michael, Owens, Karen, Tong, Vincent, Ha, Sookhee, Roy, Sophie, Kaczorowski, Gregory J., Yang, Lihu, Parmee, Emma, Garcia, Maria L., Sullivan, Kathleen, Pasternak, Alexander
Publicado no ACS Med Chem Lett (2015)